This Compelling Grey’s Anatomy Theory Suggests Jo and Britney Are Sisters – Do You Buy It?

Grey's Anatomy is coming up on its historic, record-breaking 332nd episode, making it the longest-running primetime medical drama ever, so naturally we've been on high alert for any potential twists and unexpected curveballs that showrunner Krista Vernoff might toss our way.

Now, a new theory suggests that Jo, played by Camilla Luddington, could be involved in a surprise connection - could she be related to Betty (Peyton Kennedy), also known as Britney? A new theory from Reddit user fivedaysthatsaweek makes a compelling case for it.To give you some context, in last week's episode, "I Want a New Drug," we see Meredith (Ellen Pompeo) attempting to break the record for the longest surgery ever at Grey-Sloan Memorial.

She's nearly interrupted when over 50 addicts are brought in with opiate overdoses due to taking laced pills, with one of them being Betty Britney.

Teddy (Kim Raver) is able to save Britney during surgery,

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